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Citation-first clinical tool
Azithromycin in Pregnancy and Lactation
Azithromycin is widely used in pregnancy with substantial safety data.
This tool is for educational and decision-support use only. It does not replace independent clinical judgement. Always verify against the current guideline, FDA label, or specialty reference cited below before acting. Do not enter patient identifiers (name, MRN, dates of service).
Tool
FDA PLLR + NIH LactMed
(2024)
— FDA / NIH
— read source
Primary publication: FDA PLLR (2015); NIH LactMed (continually updated)
Who this is for
- Primary care clinicians and APPs
- Obstetric and emergency clinicians
- Pharmacists supporting maternal medication review
Frequently asked questions
Does the tool give me a pregnancy category?
No. The PLLR replaced A/B/C/D/X letter categories in 2015 with a narrative summary. The tool reflects the modern narrative format.
Is LactMed authoritative?
LactMed is the U.S. National Library of Medicine's curated lactation database and is widely considered authoritative for U.S. practice.
Are there safer alternatives recommended?
When LactMed or PLLR identifies commonly considered alternatives, the tool surfaces them. Always verify against the current LactMed entry.
When should I refer to MFM or teratology?
High-risk medications (teratogens, complex polypharmacy, first-trimester exposure questions) commonly warrant specialty consultation. The tool flags this in the response.
Does it cover paternal exposures?
Most pregnancy/lactation guidance focuses on maternal exposure. Paternal-exposure concerns require a different evidence base; consult MotherToBaby or specialty resources.