Metamizole (Dipirona) Maximum Daily Dose for Adults
The maximum recommended oral daily dose of metamizole (dipirona) in adults aged ≥15 years is 4,000 mg/day. [1]
Dose Limits
- Maximum single oral dose: 1,000 mg. [1]
- Maximum dosing frequency: up to 4 times per day. [1]
- Maximum daily total: 4,000 mg/day. [1]
Age and Body Weight Considerations
- The 4,000 mg/day maximum applies to adults and adolescents aged ≥15 years. [1]
Practical Implication
Doses exceeding 4,000 mg in 24 hours should not be used for oral therapy. [1]