What is the recommended oral dose of Pedicloryl (triclofos) for children, including the dose per kilogram of body weight and maximum limits? | Rounds What is the recommended oral dose of Pedicloryl (triclofos) for children, including the dose per kilogram of body weight and maximum limits? | Rounds
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What is the recommended oral dose of Pedicloryl (triclofos) for children, including the dose per kilogram of body weight and maximum limits?

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Triclofos Sodium (Pedicloryl) Oral Pediatric Dose

Triclofos sodium (Pedicloryl) dosing for children is weight-based for younger children and fixed single-dose ranges for older children, with a maximum total dose cap. [1], [2]

Dose by Age or Weight

  • Infants 1 month to 1 year of age: 25 to 30 mg/kg as a single oral dose. [1]
  • Children 1 to 5 years of age: 250 to 500 mg as a single oral dose. [1]
  • Children 6 to 12 years of age: 0.5 to 1 g as a single oral dose. [1]

Maximum Limits

  • Total single-dose maximum: 2 g (total dose should not exceed 2 g). [2]
  • Weight-based dosing range used in labeling: 20 to 80 mg/kg, with the constraint that the total dose should not exceed 2 g. [2]

Notes on Oral Administration Context

  • Triclofos sodium is described as an oral sedative-hypnotic regimen typically given shortly before a procedure or at bedtime, consistent with use of a single-dose pediatric schedule. [1], [2]

Dose Range Consistency Across Sources

  • Reported pediatric dosing for triclofos sodium spans ~25–30 mg/kg for infants with age-based single-dose caps for older children, while labeling-based pediatric weight dosing commonly falls within 20–80 mg/kg under a 2 g maximum total dose cap. [1], [2]

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