EstroGel (estradiol gel) Maximum Pump Dose in Postmenopausal Women
EstroGel 0.06% has a single approved metered-dose pump regimen of 1 pump depression once daily, delivering 1.25 g gel per day (containing 0.75 mg estradiol). [1]
Maximum Dose in Pumps
- Maximum: 1 pump depression per day (applied to the arm). [1]
Metered-Dose Pump Conversion
- 1 pump depression = 1.25 g of EstroGel 0.06% gel containing 0.75 mg estradiol. [1]
Clinical Notes on Dose Limits
EstroGel is labeled to use the lowest effective dose for the shortest duration consistent with treatment goals and risks. [1]
Dosing Clarification for Other Estradiol Gels
Some estradiol gel products outside the United States may have different pump strengths and maximum titration schemes, which may lead to different maximum “pump” counts than EstroGel 0.06% in the U.S. [2]