Sodium valproate (valproic acid) dosing for pediatric convulsive status epilepticus
For pediatric convulsive status epilepticus treated with intravenous sodium valproate as a second-line anti-seizure medication, the recommended loading dose is 40 mg/kg IV (single dose). [1,2]
For a 2-year-old child weighing 10 kg, the calculated loading dose is 400 mg IV sodium valproate (40 mg/kg × 10 kg). [1]
Dosing calculation
- Dose (mg) = weight (kg) × 40 mg/kg = 10 kg × 40 mg/kg = 400 mg. [1]
Administration
- Sodium valproate should be administered as an IV loading dose consistent with the local pediatric status epilepticus protocol. [1]