What are the top 10 diseases associated with elevated Angiotensin-Converting Enzyme (ACE) levels? | Rounds What are the top 10 diseases associated with elevated Angiotensin-Converting Enzyme (ACE) levels? | Rounds
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What are the top 10 diseases associated with elevated Angiotensin-Converting Enzyme (ACE) levels?

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Conditions Associated With Elevated Serum Angiotensin-Converting Enzyme (ACE) Activity

Elevated serum ACE activity is most commonly associated with sarcoidosis. [1]

Clinically relevant other associations include granulomatous infections, selected malignancy, selected lysosomal and endocrine disorders, and certain inflammatory lung conditions related to environmental exposures. [1], [2]

Top Diseases and Conditions

  • Sarcoidosis [1]
  • Tuberculosis [2]
  • Leprosy [1], [2]
  • Pneumoconiosis (including environmental exposures such as asbestosis and berylliosis) [2]
  • Hodgkin lymphoma [2]
  • Gaucher disease [1]
  • Amyloidosis [1]
  • Histoplasmosis [1]
  • Hyperthyroidism [1], [2]
  • Diabetes mellitus [2]

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