Transcranial Magnetic Stimulation (rTMS) Treatment-Related Side Effects
ExoMind (ExoTMS) is a transcranial magnetic stimulation (TMS) device, so expected adverse effects are those typical of rTMS delivery. Common adverse effects are usually transient and related to stimulation site sensations and short-term neurologic or systemic symptoms. [1], [2]
Common Stimulation-Site Symptoms
- Scalp discomfort or pain at the site of magnet placement. [1], [2]
- Scalp, jaw, or facial muscle contraction or tingling during stimulation. [1], [2]
Common Neurologic or Systemic Symptoms
- Headache. [1], [2]
- Dizziness or lightheadedness. [1], [2]
- Fatigue or tiredness after treatment. [1], [2]
Less Common Treatment-Phase Effects
- Nausea. [2]
- Insomnia. [2]
Serious but Uncommon Risks
- Seizure is a potential risk of rTMS treatment, with a reported risk on the order of less than 1 in 30,000 to 1 in 50,000 during treatment sessions in one clinical service communication. [1]
- Treatment-emergent hypomanic or manic symptoms have been reported with rTMS, with one service communication citing a risk on the order of less than 1 in 100. [1]
Adverse-Event Monitoring and When to Stop
Clinical protocols for rTMS require monitoring for serious adverse events, including seizure signs, during sessions. [1]
Key Exclusions and Caution Factors
Risk of seizure may be increased by factors such as brain injury, sleep deprivation, alcohol use, or medications that lower the seizure threshold. [1]
Side Effects That Can Improve With Continued Sessions
Headache associated with stimulation often decreases as sessions continue, based on clinical service experience descriptions. [1]