What are the laboratory criteria for BioLife Plasma (Plasma Donation Center)? | Rounds What are the laboratory criteria for BioLife Plasma (Plasma Donation Center)? | Rounds
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What are the laboratory criteria for BioLife Plasma (Plasma Donation Center)?

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Last updated: July 14, 2026 · View editorial policy

Source Plasma Donor Laboratory Suitability Criteria (BioLife Plasma Centers)

BioLife Plasma centers use donor suitability criteria that include key pre-donation blood tests such as hemoglobin and total serum protein. These criteria align with U.S. FDA expectations for plasmapheresis donor suitability. [1] BioLife also performs a pre-donation medical screening that includes a blood sample on the day of donation. [2]

Hemoglobin and Hematocrit Thresholds

  • Hemoglobin must be ≥12.5 g/100 mL of blood. [1]
  • If the microhematocrit method is used, a hematocrit value of 38% is equivalent to 12.5 g/100 mL hemoglobin. [1]

Total Serum Protein Threshold

  • Total serum protein must be no less than 6.0 g/100 mL. [1]
  • Donors with quantitative total protein results <6.0 mg/100 mL are deferred until repeat testing shows acceptable values. [1]

Blood Pressure and Vital Parameters Used Alongside Laboratory Tests

  • Blood pressure must be within normal limits, with a systolic range of 90–180 mmHg and a diastolic range of 50–100 mmHg considered normal. [1]
  • Pulse rate of 50–100 beats per minute with regular rhythm is the recommended normal range. [1]

Infectious Disease Testing Relevant to Donor Eligibility

  • Donor suitability determination includes serologic testing for syphilis (STS). [1]
  • Donors must be free of diseases transmissible by blood transfusion, with specific deferral rules described by FDA donor suitability expectations. [1]

Measurement Practices on Donation Day

  • Hemoglobin/hematocrit and total serum protein are assessed as part of the day-of-donation suitability determination. [1]
  • Weight must be at least 110 lb for donation suitability. [1]

BioLife-Specific Publicly Posted Eligibility Information

  • BioLife states that a pre-donation medical screening includes vitals and a blood sample to ensure it is safe to donate that day. [2]
  • BioLife publicly indicates that local staff determine individual eligibility after medical screening. [2]

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