Lemborexant (Dayvigo) Dosing Schedule for Insomnia
Dayvigo (lemborexant) is dosed as a single tablet taken no more than once per night, immediately before going to bed, with at least 7 hours remaining before the planned time of awakening. [1] The prescription labeling does not require a fixed every-night schedule for efficacy; MedlinePlus states lemborexant is usually taken as needed (not more than once per day). [2]
Recommended Dosing Frequency
- The recommended dose is 5 mg taken no more than once per night immediately before bedtime, with at least 7 hours before the planned time of awakening. [1]
- The dose may be increased to 10 mg based on clinical response and tolerability, while still staying within the maximum recommended dose of 10 mg once daily. [1]
PRN Versus Daily Use
- Dayvigo should be taken only before bedtime and only once per night. [1]
- Lemborexant is usually taken as needed rather than on a mandatory fixed daily schedule. [2]
Timing Requirements for Therapeutic Use
- Taking Dayvigo with or soon after a meal can delay sleep onset. [1]
Practical Adherence Constraints
- Dayvigo dosing should not exceed once per night. [1]
- Dayvigo should not be taken when fewer than 7 hours remain before the planned time of awakening. [1]
Dose Escalation Within the Same Frequency Rule
- Dose escalation to 10 mg should be based on clinical response and tolerability, without exceeding once-daily maximum dosing. [1]