Ondansetron Orally Disintegrating Tablet Absorption
Ondansetron is absorbed from the gastrointestinal tract after oral administration. [1] ZOFRAN ODT is formulated to disintegrate on the tongue and then be swallowed with saliva. [1]
Swallowing Whole Considerations
If an orally disintegrating ondansetron tablet is swallowed intact, the drug still reaches the gastrointestinal tract, where ondansetron is absorbed. [1] The main impact of not dissolving in the mouth is potential delay or reduction in the speed of dosing onset, since administration instructions specify tongue dissolution prior to swallowing. [1]