Metoclopramide vs Meclizine
Metoclopramide and meclizine are different medications and are not the same drug. [1][2] Metoclopramide is a dopamine-receptor antagonist used for indications such as symptomatic gastroesophageal reflux and diabetic gastroparesis and is also used for prevention or treatment of nausea and vomiting in specific settings. [1][3] Meclizine is an antihistamine used for the prevention and treatment of nausea, vomiting, or dizziness associated with motion sickness. [2]
Mechanism of Action
Metoclopramide acts primarily by blocking dopamine (D2) receptors and related pathways involved in nausea and vomiting. [3] Meclizine acts as an antihistamine. [2]