Management of a Missed Once-Daily Itraconazole Dose
A missed dose should be taken as soon as remembered unless it is close to the time for the next dose. [1][2] A double dose should not be taken to make up for a missed itraconazole dose. [1]
Missed Dose Timing Framework
- If remembered soon after the missed time (and the next dose is not imminent), the missed itraconazole dose should be taken when remembered. [2]
- If the next dose time is close (such as when the only opportunity to take the missed dose is the next day at/near the next scheduled dose), the missed dose should be skipped and dosing should resume at the regular time. [2]
Application to Traveling Until Tomorrow
If the missed once-daily itraconazole dose will not be remembered until tomorrow when the next scheduled dose is due, the missed dose should be skipped and the next dose should be taken at the regular time. [2]
Safety Considerations
Itraconazole should not be doubled after a missed dose. [1]
When to Seek Additional Advice
Confirmation from the prescriber or pharmacist is appropriate if the exact timing relative to the next dose is unclear or if adverse effects or drug interactions are present. [1]
Core References
General patient guidance for itraconazole missed doses supports taking a missed dose when remembered, skipping it when near the next scheduled dose, and avoiding double dosing. [1][2]