Amlodipine-Associated Dysuria
Amlodipine can cause dysuria as an adverse reaction. [1]
Adverse Reaction Evidence
Amlodipine prescribing information lists dysuria under events occurring in <0.1% of patients. [1]
Drug-Related Urinary Symptoms
Amlodipine labeling also lists other urinary system effects, including micturition frequency, micturition disorder, and nocturia. [1]
Clinical Interpretation of Dysuria on Amlodipine
Dysuria after starting amlodipine should raise consideration of a medication adverse reaction. [1]
Evaluation Considerations for Dysuria
Other causes of dysuria (including urinary tract infection) should be assessed because dysuria is a symptom and not a diagnosis. [2]
When to Seek Urgent Care
Urgent evaluation is indicated for fever, flank pain, vomiting, gross hematuria, or inability to urinate. [2]
Management Approach When Dysuria Occurs
If dysuria appears temporally related to amlodipine, discontinuation or substitution of the medication should be considered in conjunction with the prescriber. [1]
Relevant Patient Safety Resources
A suspected adverse reaction to amlodipine can be reported to FDA MedWatch. [2]